Search results for "Statins"
PCSK9 inhibitor appears more effective than ezetimibe for short-term LDL lowering in small, randomized trial
The authors of an accompanying editorial noted that PCSK9 inhibitors like evolocumab are not approved for the indication in the trial and have not yet been shown to reduce cardiovascular events.
https://immattersacp.org/weekly/archives/2016/04/05/5.htm
5 Apr 2016
Guidance issued on nonstatin therapies for cholesterol lowering
The goal of the decision pathway was to provide practical guidance for clinicians and patients in situations not covered by the 2013 ACC/AHA guideline until new clinical guidelines on the topic are published.
https://immattersacp.org/weekly/archives/2016/04/05/4.htm
5 Apr 2016
There are challenges when translating research to practice
Despite convincing results for many health care interventions, translating evidence from research into clinical practice is often challenging. What works in a research environment may not function in practice.
https://immattersacp.org/archives/2016/04/policy.htm
1 Apr 2016
MKSAP Quiz: Evaluation during a routine examination
A 74-year-old woman is evaluated during a routine examination. Her medical history is significant for hypertension and obesity. She is a former smoker, stopping 5 years ago. Medications are amlodipine, lisinopril, and aspirin. Following a physical exam and ankle-brachial index score, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2016/07/19/3.htm
19 Jul 2016
Societies stress shared decision making in updated lipids performance measures
Better patient outcomes are realized only if patients agree with, act on, and adhere to their doctors' advice for 5 to 10 years, but up to half of patients stop statins at 1 to 2 years.
https://immattersacp.org/weekly/archives/2015/12/15/5.htm
15 Dec 2015
NAFLD treatment starts with weight loss, then other modes
Nonalcoholic fatty liver disease (NAFLD), which accounts for 30% to 40% of chronic liver disease in the U.S. today, is the hepatic manifestation of the metabolic syndrome and is associated with sleep apnea, cardiovascular disease, and diabetes.
https://immattersacp.org/archives/2016/07/NAFLD.htm
1 Jul 2016
MKSAP Quiz: 10-month history of generalized weakness
A 61-year-old man is evaluated for a 10-month history of generalized weakness. He reports no pain or myalgia. History is significant for hypercholesterolemia treated with a stable dose of simvastatin for the past 3 years. Following a physical exam, lab studies, and a chest radiograph, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2016/07/12/3.htm
12 Jul 2016
Minding your P's and M's
In medicine, internists need to mind not just their "P's and Q's" but their "P's and M's," that is, evidence-based practice and evidence-based medicine.
https://immattersacp.org/archives/2017/05/presidents.htm
1 May 2017
CA-125-guided therapy may improve outcomes for acute heart failure vs. standard of care
A multicenter randomized trial compared postdischarge therapy in patients who were hospitalized for acute heart failure and had high CA-125 levels.
https://immattersacp.org/weekly/archives/2016/08/16/4.htm
16 Aug 2016
Age only one consideration in post-MI drug therapy
To determine the best therapy for elderly patients after a heart attack, physicians should get to know their goals for their lives.
https://immattersacp.org/archives/2020/09/age-only-one-consideration-in-post-mi-drug-therapy.htm
1 Sep 2020