Search results for "Kidney function"
MKSAP Quiz: Painless intermittent bloody urine
A 56-year-old man is evaluated for painless intermittent bloody urine of 6 weeks' duration. History is significant for granulomatosis with polyangiitis (formerly known as Wegener granulomatosis) diagnosed 10 years ago, which is now in remission; he was treated with prednisone for 3 years and oral cyclophosphamide for 1 year. Following a physical exam, lab studies, and chest radiograph, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/weekly/archives/2018/06/12/3.htm
12 Jun 2018
Osteoarthritis can ease with easy changes
An optimal regimen starting with nonpharmacologic measures can help patients achieve notable relief.
https://immattersacp.org/archives/2021/05/osteoarthritis-can-ease-with-easy-changes.htm
1 May 2021
Keep a close eye on the kidneys in diabetes
Screening and adherence to best prescribing practices offer two key ways to prevent or slow the progression of chronic kidney disease in patients with diabetes.
https://immattersacp.org/archives/2020/09/keep-a-close-eye-on-the-kidneys-in-diabetes.htm
1 Sep 2020
Cardiovascular safety of febuxostat and allopurinol compared in patients with gout and CVD
In a modified intention-to-treat analysis, the primary end point of first occurrence of cardiovascular death, nonfatal myocardial infarction, nonfatal stroke, or urgent revascularization for unstable angina occurred in 10.8% of patients taking febuxostat and in 10.4% of patients taking allopurinol (hazard ratio, 1.03).
https://immattersacp.org/weekly/archives/2018/03/20/4.htm
20 Mar 2018
MKSAP Quiz: Exacerbations of heart failure
A 68-year-old man is evaluated at a follow-up appointment. He has a 7-year history of heart failure secondary to ischemic cardiomyopathy. Over the past 6 months, he has had three hospitalizations for exacerbations of his heart failure. He currently has exertional dyspnea while getting dressed, and his maximal activity level is limited to riding to the store with his wife but staying in the car. Following a physical exam and lab studies, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2018/03/13/3.htm
13 Mar 2018
MKSAP quiz: Intermittent fever, sweats, fatigue
A 35-year-old woman is evaluated for intermittent fever, sweats, fatigue, and dull midchest pain of 2 weeks' duration. Medical history is significant for liver transplantation 6 months ago for primary biliary cirrhosis; she was seronegative for cytomegalovirus and Epstein-Barr virus, and her donor was positive for both. Results of pretransplant testing for tuberculosis were negative. Following a physical exam, lab studies, and chest radiograph, what is the most likely cause of her clinical findings?
https://immattersacp.org/weekly/archives/2018/01/30/3.htm
30 Jan 2018
MKSAP Quiz: evaluation for acute kidney injury
A 57-year-old man is evaluated for a diagnosis of acute kidney injury. He was diagnosed with gastroesophageal reflux disease 3 weeks ago and was prescribed omeprazole. Several days ago he noticed lower extremity swelling and decreased frequency of urination. Laboratory evaluation showed a serum creatinine level of 2.2 mg/dL (194.5 µmol/L). Medical history is otherwise unremarkable. Following a physical exam and discontinuing omeprazole, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2016/09/13/3.htm
13 Sep 2016
Correcting medicine's use of race in clinical algorithms
Recent efforts have pushed institutions to reconsider the use of race not just in estimating kidney function, but in a variety of algorithms and scores.
https://immattersacp.org/archives/2021/05/correcting-medicines-use-of-race-in-clinical-algorithms.htm
1 May 2021
MKSAP Quiz: Follow-up examination for diabetes
A 54-year-old woman is evaluated during a follow-up examination. She has a 22-year history of type 2 diabetes mellitus complicated by sensory neuropathy and proliferative retinopathy, for which she has received laser photocoagulation. She also has hypertension and hyperlipidemia. Medications are metformin, glipizide, atorvastatin, and lisinopril, 20 mg/d. Following a physical exam and lab studies, what is the most appropriate management of this patient's hypertension?
https://immattersacp.org/weekly/archives/2016/12/20/3.htm
20 Dec 2016
GLP-1 receptor agonists may offer kidney protection in patients with type 2 diabetes
An industry-conducted pooled analysis of two large trials of glucagon-like peptide-1 (GLP-1) receptor agonists found that both semaglutide and liraglutide slowed kidney function decline, with semaglutide appearing to have the greatest effect.
https://immattersacp.org/weekly/archives/2021/12/21/2.htm
21 Dec 2021