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New drug treats cancer based on biomarker, not location

This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2017/07/new-drug-treats-cancer-based-on-biomarker-not-location.htm
1 Jul 2017

Short-term oral corticosteroids no better than placebo at treating lower respiratory tract infection symptoms, study finds

Researchers randomized 199 patients to receive two 20-mg prednisolone tablets and 202 patients to receive placebo once daily for five days, with primary outcomes of duration of moderately bad or worse cough and mean symptom severity on days two and four.
https://immattersacp.org/weekly/archives/2017/08/29/3.htm
29 Aug 2017

Insulin cartridge holders recalled, HCV drug approved

This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2017/09/insulin-cartridge-holders-recalled-hcv-drug-approved.htm
1 Sep 2017

10% of those who use opioids account for the vast majority of use

A recent study examined a commercial database of pharmacy claims for more than 20 million privately insured adults without cancer who were continuously enrolled for at least one calendar year between 2001 and 2013 and filled at least one prescription for an opioid.
https://immattersacp.org/weekly/archives/2017/09/12/4.htm
12 Sep 2017

High-risk outpatients with acute respiratory illness infrequently prescribed antivirals for influenza, study finds

Factors associated with antiviral treatment were early presentation to care, presence of fever, positive influenza test result, and presentation within the 2013–2014 and 2014–2015 seasons.
https://immattersacp.org/weekly/archives/2017/10/31/2.htm
31 Oct 2017

DynaMed Plus Quiz: Shortness of breath

A 40-year-old trophy-winning professional knitter reports increasing shortness of breath and dry cough for the past week, as well as hoarseness and throat pain for the past three days. Upon questioning, she reports feeling “feverish” and being unusually tired of late. Following a review of systems, physical exam, and lab tests, what is the most likely diagnosis?
https://immattersacp.org/archives/2017/11/dynamed-plus-quiz-shortness-of-breath.htm
1 Nov 2017

MKSAP Quiz: Routine follow-up for very severe COPD

A 75-year-old man is seen for routine follow-up for very severe COPD. He has constant dyspnea and air hunger and spends most of the day in a chair. He has had no change in baseline cough and sputum production. He has had multiple COPD exacerbations that required ICU admission and intubation. He has not benefited from pulmonary rehabilitation in the past. What is the most appropriate management?
https://immattersacp.org/weekly/archives/2017/11/07/3.htm
7 Nov 2017

MKSAP Quiz: 5-day history of a lesion

A 31-year-old woman is evaluated for a 5-day history of a nonpainful cutaneous lesion on the back of her left hand. She works as a packer in a parcel distribution center. She does not recall injury to this area and reports no unusual employment or recreational exposures. She has not had fever, cough, shortness of breath, headache, chest discomfort, or gastrointestinal symptoms. Yesterday, two coworkers were evaluated for similar lesions. Her husband has recently been prescribed an antibiotic after being diagnosed with a “boil” from which methicillin-resistant Staphylococcus aureus was cultured. Her only medication is an oral contraceptive pill. What is the most appropriate management?
https://immattersacp.org/archives/2018/02/mksap-quiz-5-day-history-of-a-lesion.htm
1 Feb 2018

Gout drug concerns; monthly buprenorphine injection OK'd

This column reviews details on recent recalls, warnings, and approvals.
https://immattersacp.org/archives/2018/02/gout-drug-concerns-monthly-buprenorphine-injection-okd.htm
1 Feb 2018

MKSAP Quiz: Follow-up for idiopathic pulmonary fibrosis

A 58-year-old man is evaluated in follow-up for idiopathic pulmonary fibrosis (IPF), which was diagnosed 2 years ago. He has cough and shortness of breath and now requires supplemental oxygen at rest. Previous evaluations have not identified any cause for his symptoms other than progressive IPF. Following a physical exam, pulmonary exam, and 6-minute walk test, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2018/02/27/3.htm
27 Feb 2018

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