Search results for "Cardiovascular events"
Location, distribution of calcium may improve coronary artery calcium scoring for cardiovascular events
Considerable heterogeneity existed between the coronary artery calcium score and number of vessels with coronary artery calcium, and adding the number of vessels with coronary artery calcium significantly improved prediction of coronary events in survival analysis, area under the curve analysis, and net reclassification improvement analysis.
https://immattersacp.org/weekly/archives/2016/04/19/4.htm
19 Apr 2016
Task Force recommends aspirin for primary prevention of CVD, colorectal cancer
The Task Force recommended that low-dose aspirin be initiated for the primary prevention of CVD and colorectal cancer in adults ages 50 to 59 years who have a 10% or greater 10-year CVD risk, are not at increased risk for bleeding, have a life expectancy of at least 10 years, and are willing to take low-dose aspirin daily for at least 10 years.
https://immattersacp.org/weekly/archives/2016/04/12/1.htm
12 Apr 2016
Statin treatment reduced cardiovascular events more than hypertension drugs in intermediate-risk patients, study finds
An accompanying editorial said that the results of this trial support the benefits of statins for primary prevention and a risk-based approach to prescribing, rather than one based on LDL levels.
https://immattersacp.org/weekly/archives/2016/04/05/1.htm
5 Apr 2016
PCSK9 inhibitor appears more effective than ezetimibe for short-term LDL lowering in small, randomized trial
The authors of an accompanying editorial noted that PCSK9 inhibitors like evolocumab are not approved for the indication in the trial and have not yet been shown to reduce cardiovascular events.
https://immattersacp.org/weekly/archives/2016/04/05/5.htm
5 Apr 2016
MKSAP Quiz: Cardiac risk assessment
A 58-year-old man is evaluated during a routine appointment and asks for advice on cardiac risk assessment. He does not have any current cardiac symptoms, exercises 4 days per week, and has never smoked. He has no chronic health issues and takes no medications. He has no known drug allergies. Results of the physical examination are normal. Following cardiovascular risk calculation, what test should be performed next?
https://immattersacp.org/weekly/archives/2016/04/05/3.htm
5 Apr 2016
Shifting standards for hypertension
New hypertension guidelines are being developed by the American Heart Association (AHA) and the American College of Cardiology (ACC) that will incorporate new study results. At issue is how these results apply to the many types of patients who walk through the office door, including those with diabetes.
https://immattersacp.org/archives/2016/03/hypertension.htm
1 Mar 2016
MKSAP Quiz: Evaluation of risk for cardiovascular disease
A 49-year-old man is evaluated during a routine examination. He is asymptomatic but is concerned about his risk for cardiovascular disease. Medical history is notable for hypertension. He is a nonsmoker, and he works as an executive at a highly successful company. Family history is noncontributory. His only medication is hydrochlorothiazide. Following a physical exam and cholesterol and glucose testing, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2016/02/09/3.htm
9 Feb 2016
Warning on HCV treatments; more cancer drugs approved
This update also covers a warning that combination drugs can cause serious liver injury and approval of new drugs for metastatic non-small-cell lung cancer that has progressed after other treatments.
https://immattersacp.org/archives/2016/01/fda.htm
1 Jan 2016
SPRINT finds lower systolic BP targets associated with better outcomes in nondiabetic adults at high CV risk
The trial was stopped early because of a significantly lower rate of myocardial infarction, other types of acute coronary syndromes, stroke, heart failure, or death from CV causes in the intensive treatment group (systolic blood pressure target <120 mm Hg).
https://immattersacp.org/weekly/archives/2015/11/17/1.htm
17 Nov 2015
Study finds masked and white coat hypertension prevalent and associated with higher risk of adverse cardiovascular events
Both white coat hypertension and masked hypertension were independently associated with increased biomarkers for organ damage, as well as higher risk of cardiovascular events compared with normal blood pressure, even after adjustment for traditional cardiovascular risk factors.
https://immattersacp.org/weekly/archives/2015/11/10/1.htm
10 Nov 2015