Search results for "Anticoagulation"
Prescription NSAIDs associated with heart failure risk, study finds
A 19% increased risk for hospital admission for heart failure was found to be associated with any use of NSAIDs in the preceding 14 days versus past use of any NSAIDs. Diclofenac, ibuprofen, indomethacin, ketorolac, naproxen, nimesulide, piroxicam, etoricoxib, and rofecoxib were associated with increased risk for hospital admission.
https://immattersacp.org/weekly/archives/2016/10/04/1.htm
4 Oct 2016
Anticoagulation not superior to placebo for calf DVT in low-risk patients, may increase bleeding risk
The randomized, double-blind, placebo-controlled trial examined a composite measure of extension of calf deep venous thrombosis (DVT) to proximal veins, contralateral proximal DVT, and symptomatic pulmonary embolism in a modified intention-to-treat population.
https://immattersacp.org/weekly/archives/2016/11/15/6.htm
15 Nov 2016
Anticoagulation not superior to placebo for calf DVT in low-risk patients, may increase bleeding risk
The randomized, double-blind, placebo-controlled trial examined a composite measure of extension of calf deep venous thrombosis (DVT) to proximal veins, contralateral proximal DVT, and symptomatic pulmonary embolism in a modified intention-to-treat population.
https://immattersacp.org/weekly/archives/2016/11/22/6.htm
22 Nov 2016
Low-molecular-weight heparin may not prevent VTE after knee arthroscopy or lower-leg casting, studies find
The Prevention of Thrombosis after Knee Arthroscopy (POT-KAST) and the Prevention of Thrombosis after Lower Leg Plaster Cast (POT-CAST) trials used the same methods and design to compare a prophylactic dose of low-molecular-weight heparin or no anticoagulant therapy.
https://immattersacp.org/weekly/archives/2016/12/13/4.htm
13 Dec 2016
Off-label dosing of non-vitamin K anticoagulants associated with worse outcomes
Overdosing with non-vitamin K anticoagulants was associated with increased all-cause mortality compared with recommended doses, while underdosing was associated with increased risk of cardiovascular hospitalization.
https://immattersacp.org/weekly/archives/2016/12/20/2.htm
20 Dec 2016
MKSAP Quiz: Management of joint pain
A 67-year-old woman is evaluated during a routine examination. She has a history of hip and knee pain related to degenerative joint disease. The joint pain is now well controlled with diclofenac, which was started 3 months ago. She does not have any gastrointestinal symptoms, and she takes the diclofenac with food most of the time. What is the most appropriate management?
https://immattersacp.org/weekly/archives/2017/06/20/3.htm
20 Jun 2017
Major bleeding, mortality risks after VTE similar on DOACs or warfarin
The risk of major bleeding and of death was similar for patients taking direct oral anticoagulants compared to those taking warfarin.
https://immattersacp.org/weekly/archives/2017/10/24/4.htm
24 Oct 2017
Early oral anticoagulation in afib may protect against dementia
Taking anticoagulant treatment at baseline was associated with a 29% lower risk of dementia than not receiving anticoagulant treatment and a 48% lower risk when analyzed on treatment.
https://immattersacp.org/weekly/archives/2017/10/31/1.htm
31 Oct 2017
MKSAP Quiz: Anticoagulation management during pregnancy
A 26-year-old woman with a mechanical mitral valve prosthesis visits to discuss anticoagulation management during pregnancy. Her last menstrual period was 6 weeks ago and her pregnancy was confirmed by laboratory testing in the office. Her mitral valve was replaced 5 years ago. Her medications are low-dose aspirin, metoprolol, and warfarin (4 mg/d). Which anticoagulation regimen will provide the greatest protection against thromboembolism during her pregnancy?
https://immattersacp.org/weekly/archives/2017/11/21/3.htm
21 Nov 2017
Meta-analysis compares treatments for stroke prevention in afib
Risk for stroke or systemic embolism was lower with apixaban (5 mg twice daily), dabigatran (150 mg twice daily), edoxaban (60 mg twice daily), and rivaroxaban (20 mg twice daily) than warfarin, a study found.
https://immattersacp.org/weekly/archives/2017/12/05/1.htm
5 Dec 2017