Search results for "Statins"
CA-125-guided therapy may improve outcomes for acute heart failure vs. standard of care
A multicenter randomized trial compared postdischarge therapy in patients who were hospitalized for acute heart failure and had high CA-125 levels.
https://immattersacp.org/weekly/archives/2016/08/16/4.htm
16 Aug 2016
MKSAP Quiz: 3-month history of gradually progressive abdominal distention
A 68-year-old woman is evaluated for a 3-month history of gradually progressive abdominal distention. Her medical history is notable for a 20-year history of obesity, type 2 diabetes mellitus, hyperlipidemia, and hypertension. She also has had a 10-year history of elevation of serum aminotransferase levels, which was attributed to nonalcoholic fatty liver disease. She does not consume alcohol. Her medications are metformin, lisinopril, low-dose aspirin, and simvastatin. Following physical and abdominal exams, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2016/08/09/3.htm
9 Aug 2016
MKSAP Quiz: Evaluation during a routine examination
A 74-year-old woman is evaluated during a routine examination. Her medical history is significant for hypertension and obesity. She is a former smoker, stopping 5 years ago. Medications are amlodipine, lisinopril, and aspirin. Following a physical exam and ankle-brachial index score, what is the most appropriate management?
https://immattersacp.org/weekly/archives/2016/07/19/3.htm
19 Jul 2016
MKSAP Quiz: 10-month history of generalized weakness
A 61-year-old man is evaluated for a 10-month history of generalized weakness. He reports no pain or myalgia. History is significant for hypercholesterolemia treated with a stable dose of simvastatin for the past 3 years. Following a physical exam, lab studies, and a chest radiograph, what is the most likely diagnosis?
https://immattersacp.org/weekly/archives/2016/07/12/3.htm
12 Jul 2016
Pearls for lowering lipids
New guidelines recommend basing treatment decisions on levels of risk rather than LDL targets.
https://immattersacp.org/archives/2016/07/lipids.htm
1 Jul 2016
NAFLD treatment starts with weight loss, then other modes
Nonalcoholic fatty liver disease (NAFLD), which accounts for 30% to 40% of chronic liver disease in the U.S. today, is the hepatic manifestation of the metabolic syndrome and is associated with sleep apnea, cardiovascular disease, and diabetes.
https://immattersacp.org/archives/2016/07/NAFLD.htm
1 Jul 2016
Optimizing medical therapy after stroke
Stroke survivors often leave the hospital with new prescriptions and substantial confusion about how, or even whether, to take them. This leaves internists with the sometimes formidable job of evaluating, prescribing, or tweaking these regimens, identifying and managing adverse effects, and reinforcing education about treatment risks, benefits, and adherence.
https://immattersacp.org/archives/2016/06/stroke.htm
1 Jun 2016
Sustained change a challenge for health
Health-linked incentives have become increasingly common, particularly by employers. But researchers are still trying to sort out what type and design of incentives are most effective and whether they hold significant potential to achieve both short- and long-term behavioral changes.
https://immattersacp.org/archives/2016/05/lifestyle.htm
1 May 2016
Statin treatment reduced cardiovascular events more than hypertension drugs in intermediate-risk patients, study finds
An accompanying editorial said that the results of this trial support the benefits of statins for primary prevention and a risk-based approach to prescribing, rather than one based on LDL levels.
https://immattersacp.org/weekly/archives/2016/04/05/1.htm
5 Apr 2016
PCSK9 inhibitor appears more effective than ezetimibe for short-term LDL lowering in small, randomized trial
The authors of an accompanying editorial noted that PCSK9 inhibitors like evolocumab are not approved for the indication in the trial and have not yet been shown to reduce cardiovascular events.
https://immattersacp.org/weekly/archives/2016/04/05/5.htm
5 Apr 2016