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NAFLD treatment starts with weight loss, then other modes

Nonalcoholic fatty liver disease (NAFLD), which accounts for 30% to 40% of chronic liver disease in the U.S. today, is the hepatic manifestation of the metabolic syndrome and is associated with sleep apnea, cardiovascular disease, and diabetes.
https://immattersacp.org/archives/2016/07/NAFLD.htm
1 Jul 2016

HCV patients being treated for opioid addiction appear to benefit from antiviral therapy

Patients with hepatitis C virus (HCV) infection who were receiving opioid-agonist therapy (such as methadone or buprenorphine) and treatment with elbasvir-grazoprevir had high rates of sustained virologic response regardless of continued drug use, an industry-funded study found.
https://immattersacp.org/weekly/archives/2016/08/09/4.htm
9 Aug 2016

Time to curb the rising costs of prescription drugs

The U.S. will see the largest increase in per capita costs in pharmaceuticals among developed markets through 2018. The CREATES Act: Ending Regulatory Abuse, Protecting Consumers, and Ensuring Drug Price Competition would approve federal and state regulation on costs to allow for return on investment by manufacturers but ensure affordability for patients.
https://immattersacp.org/archives/2016/10/presidents.htm
1 Oct 2016

HIV and chronic HBV/HCV co-infection may increase non-Hodgkin's lymphoma risk

Co-infected patients with poor immune status or restoration are at high risk for non-Hodgkin's lymphoma and death and deserve high priority for access to well-tolerated, interferon-free, direct-acting antiviral treatment programs, study authors noted.
https://immattersacp.org/weekly/archives/2016/10/18/2.htm
18 Oct 2016

Adult immunization schedule released for 2017

The Advisory Committee on Immunization Practices has released its 2017 Recommended Immunization Schedule for adults, with changes to influenza, human papillomavirus, hepatitis B, and meningococcal vaccinations.
https://immattersacp.org/weekly/archives/2017/02/07/4.htm
7 Feb 2017

Managing medication adherence

That most nonadherent patients are willfully rejecting doctors' orders might seem shocking. But physicians have to accept it in order to encourage patients to accept their advice. Digital health tools may offer potential aids in solving matters of adherence.
https://immattersacp.org/archives/2017/03/adherence.htm
1 Mar 2017

MKSAP Quiz: 8-year history of joint pain

A 50-year-old man is evaluated for an 8-year history of joint pain, particularly in the hands, and progressively worsening fatigue. Medical history is otherwise unremarkable. He takes ibuprofen as needed. There are swelling and tenderness of the second and third metacarpophalangeal (MCP) joints bilaterally, and tenderness but no swelling of the fourth and fifth MCP joints bilaterally. There is bony hypertrophy of the first MCP joints and knees bilaterally. The proximal interphalangeal joints and wrists are normal. Following a physical exam, lab studies, and a radiograph, what is the most appropriate diagnostic test to perform next?
https://immattersacp.org/archives/2017/05/mksap.htm
1 May 2017

ACP and the American Academy of HIV Medicine collaborate on new guide to hepatitis C testing

The new guide includes a summary of the latest testing recommendations; diagnostic, billing, and laboratory codes for testing; resources for referrals to HCV-experienced clinicians; and information on patient interactions, education, conversations, and case examples.
https://immattersacp.org/weekly/archives/2017/05/16/5.htm
16 May 2017

HCV treatment by NPs, PCPs appears safe, effective as that provided by subspecialists

Reversing restrictions that limit prescribing of direct-acting antivirals might allow rapid escalation of safe, effective therapy for hepatitis C virus (HCV) infection and could improve the care of patients, study authors noted.
https://immattersacp.org/weekly/archives/2017/08/08/2.htm
8 Aug 2017

MKSAP Quiz: 6-week history of blisters

A 55-year-old man is evaluated for a 6-week history of blisters on his hands. The blisters are tender, break easily after they develop, and occur in different regions on the backs of his hands. Medical history is notable for alcoholic liver disease. The patient does not use tobacco but drinks 6 beers daily. He takes no medications. Following a physical exam, what is the most likely diagnosis?
https://immattersacp.org/archives/2017/09/mksap-quiz-6-week-history-of-blisters.htm
1 Sep 2017

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