Search results for "Gout"
Internationally developed gout guidelines seek to improve clinical practice
Ten recommendations for the diagnosis and management of patients with gout have been developed by a multinational group with the aim of improving daily clinical practice.
https://immattersacp.org/weekly/archives/2014/01/14/2.htm
14 Jan 2014
MKSAP Quiz: 2-year history of knee osteoarthritis
A 64-year-old man is evaluated for a 2-year history of knee osteoarthritis. He has bilateral knee pain that worsens with walking. He has tried topical therapies, physical therapy, and acetaminophen, none of which has provided relief. The patient also has peripheral vascular disease, hyperlipidemia, and hypertension. Medications are hydrochlorothiazide, pravastatin, and a daily aspirin. Following a physical exam, lab results, and radiographs of the knees, what is the most appropriate treatment for this patient?
https://immattersacp.org/weekly/archives/2014/06/17/3.htm
17 Jun 2014
Nighttime gout attack risk may be twice as much as in daytime
The risk of acute gout attacks was more than twice as high during the night or early morning hours than the day, even among those who did not consume alcohol and had a low purine intake during the 24 hours prior to the attack, a study found.
https://immattersacp.org/weekly/archives/2014/12/16/5.htm
16 Dec 2014
MKSAP Quiz: Gout with flares
This week's quiz asks readers to determine the appropriate next step in management for a 59-year-old man with a 6-month history of gout, hypersensitivity to allopurinol, and more frequent gout flares.
https://immattersacp.org/weekly/archives/2015/09/15/3.htm
15 Sep 2015
Corticosteroids may be viable first-line alternative to NSAIDs for acute gout
The study provides evidence that oral corticosteroids are as effective at treating pain and as acceptable to patients as non-steroidal anti-inflammatory drugs, and that they should be considered as a first-line alternative in the treatment of patients with acute gout.
https://immattersacp.org/weekly/archives/2016/02/23/4.htm
23 Feb 2016
Warning about different doses for 2 forms of posaconazole
This update covers a warning that differences in dosing regimens between the 2 oral formulations of posaconazole (Noxafil) have resulted in dosing errors.
https://immattersacp.org/archives/2016/03/fda.htm
1 Mar 2016
Noninvasive treatment almost always best for knee pain
Knee symptoms are the most common musculoskeletal reason why patients visit their doctors, and in most cases, except when breaks or infection is suspected, physicians should recommend the use of nonsurgical treatments first.
https://immattersacp.org/archives/2016/04/knees.htm
1 Apr 2016
Clinical practice guideline for acute gout recommends corticosteroids, NSAIDs, low-dose colchicine
For diagnosis, a separate guideline recommended that physicians use synovial fluid analysis when clinical judgment indicates that diagnostic testing is necessary in patients with possible gout.
https://immattersacp.org/weekly/archives/2016/11/01/1.htm
1 Nov 2016
MKSAP Quiz: follow-up visit for gout
A 55-year-old man is evaluated during a follow-up visit for gout. Two years ago, he had been treated with allopurinol and developed a hypersensitivity reaction. Over the past several months, he has had recurrent attacks of acute, episodic swelling of the first metatarsophalangeal joints with increasing involvement of other joints, including the ankles and knees. Laboratory studies showed significant hyperuricemia. History is also significant for Crohn disease, hypertension, chronic kidney disease (estimated glomerular filtration rate of 55 mL/min/1.73 m2), and nonalcoholic fatty liver disease. Current medications are diltiazem and azathioprine, which he has been taking for the past 9 months. Which of these is a contraindication to the use of febuxostat in this patient?
https://immattersacp.org/weekly/archives/2017/01/24/3.htm
24 Jan 2017
PERSPECTIVES 4 ACP Internist Last November, the debate over ...
internal medicine and rheumatology. Last year, ACP released new evidence-based guidelinesoffering recommendations on diagnosis and treatment of gout, but it was a lack of a recom-mendation that actually caused ... Based on Tissue plasminogen activator for acute ischemic stroke. The NINDS rt-PA Stroke Study Group.
https://immattersacp.org/archives/2017/04/acpi-201704-dynamed_t1.pdf
23 Mar 2017