Search results for "Fracture risk"
NAFLD treatment starts with weight loss, then other modes
Nonalcoholic fatty liver disease (NAFLD), which accounts for 30% to 40% of chronic liver disease in the U.S. today, is the hepatic manifestation of the metabolic syndrome and is associated with sleep apnea, cardiovascular disease, and diabetes.
https://immattersacp.org/archives/2016/07/NAFLD.htm
1 Jul 2016
Guidance issued for long-term bisphosphonate use
The authors noted that the risk of atypical femoral fractures is low, with an incidence of up to 50 per 100,000 person-years during the first 5 years of bisphosphonate use, resulting in a clear positive benefit/risk ratio within this time frame.
https://immattersacp.org/weekly/archives/2016/01/26/1.htm
26 Jan 2016
Warning on HCV treatments; more cancer drugs approved
This update also covers a warning that combination drugs can cause serious liver injury and approval of new drugs for metastatic non-small-cell lung cancer that has progressed after other treatments.
https://immattersacp.org/archives/2016/01/fda.htm
1 Jan 2016
Fall, fracture risk may be increased with prostate-selective alpha antagonists in older men
Men 66 years of age and older who had filled a first outpatient prescription for tamsulosin, alfuzosin, or silodosin were compared with men who had not.
https://immattersacp.org/weekly/archives/2015/11/03/2.htm
3 Nov 2015
New warnings added on multiple diabetes drugs
This update also covers a risk evaluation and mitigation strategy for liraglutide and approval of a new PCSK9 inhibitor.
https://immattersacp.org/archives/2015/11/fda.htm
1 Nov 2015
Calcium intake does not appear to decrease fracture risk in older patients
A new study indicates that calcium supplements with or without vitamin D do not protect older people in general from fractures, and an editorialist suggests that 700 to 800 mg of dietary calcium daily for adults is probably enough.
https://immattersacp.org/weekly/archives/2015/10/06/1.htm
6 Oct 2015
SSRIs may be associated with increased fracture risk in middle-aged women without mental disorders
Women without mental illness who started SSRIs and a cohort of women who started H2 antagonists or proton-pump inhibitors (without SSRIs) were compared, with a main study outcome of hip, humerus, radius, or ulna fractures 1 or more days after starting therapy.
https://immattersacp.org/weekly/archives/2015/07/07/2.htm
7 Jul 2015
MKSAP Quiz: maintaining bone health
A 54-year-old woman comes to the office for advice regarding maintaining bone health. She has no history of fracture. The patient recently had a lumpectomy and radiation therapy to treat breast cancer, is currently taking tamoxifen, and will begin taking an aromatase inhibitor in 2 months. She underwent menopause at age 52 years and has persistent hot flushes. Her risk factors for osteoporosis include a slim body habitus and a mother who had a hip fracture at age 67 years. Following a physical exam, lab results and a dual-energy x-ray absorptiometry scan, what pharmacologic agents can be started in this patient?
https://immattersacp.org/weekly/archives/2015/03/10/3.htm
10 Mar 2015
Age, bone mineral density may predict 5-year fracture risk after stopping bisphosphonate
When postmenopausal women stop bisphosphonate therapy, their age and hip bone mineral density (BMD) can help predict the likelihood of fractures over the next 5 years, a study found.
https://immattersacp.org/weekly/archives/2014/05/13/6.htm
13 May 2014
Repeat BMD screens unlikely to change osteoporosis management
Older patients who aren't being treated for osteoporosis may not benefit from frequent repetition of bone mineral density (BMD) testing, a new study found.
https://immattersacp.org/weekly/archives/2013/10/01/4.htm
1 Oct 2013