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Osteoporosis associated with significant five-year risk of hip fracture in women 80 years and older

Women with osteoporosis had similar mortality risk, but much higher rates of hip fracture, compared to those without osteoporosis but with other risk factors for fracture.
https://immattersacp.org/weekly/archives/2019/06/25/4.htm
25 Jun 2019

Guideline recommends pharmacologic treatment of osteoporosis in postmenopausal women at high fracture risk

Bisphosphonates are recommended for initial treatment, although ibandronate is not recommended for reducing nonvertebral or hip fracture risk, the clinical practice guideline from the Endocrine Society stated.
https://immattersacp.org/weekly/archives/2019/04/02/4.htm
2 Apr 2019

Association between antidepressants and hip fracture in elderly patients may not be causal

Antidepressant users had more than twice as many hip fractures as nonusers, but this was true both in the year before and the year after starting antidepressant therapy, and the association was strongest immediately before antidepressant initiation.
https://immattersacp.org/weekly/archives/2019/01/08/1.htm
8 Jan 2019

Canagliflozin may not increase fracture risk in patients at low risk for fractures

Although canagliflozin has been linked to decreased bone mineral density, patients with type 2 diabetes who initiated the drug had similar risk of a first fracture as those who started a glucagon-like peptide-1 receptor agonist.
https://immattersacp.org/weekly/archives/2019/01/08/2.htm
8 Jan 2019

Osteoporosis treatment often not started after hip fracture in elderly patients, study finds

The study found a continuous decline in starting osteoporosis treatment after hip fracture from 2004 to 2015, as well as a clinically meaningful reduction in rate of subsequent nonvertebral fracture in patients who did begin treatment versus those who did not.
https://immattersacp.org/weekly/archives/2018/07/24/4.htm
24 Jul 2018

Factor frailty into preop assessment

There's no real consensus definition when it comes to assessing frailty perioperatively, but there are risk calculators and risk indices available to help.
https://immattersacp.org/archives/2018/07/factor-frailty-into-preop-assessment.htm
1 Jul 2018

MKSAP Quiz: Evaluation for a new-patient visit

A 55-year-old woman is evaluated for a new-patient visit. Medical history is significant for an eating disorder. Although she has maintained a normal weight for the past 20 years, she notes that prior to that time her weight would fluctuate in a range correlating with BMIs of 17 to 19. Family history is significant for postmenopausal osteoporosis in her mother. Following a physical exam and lab studies, what is the most appropriate management of this patient?
https://immattersacp.org/weekly/archives/2018/03/27/3.htm
27 Mar 2018

Antidepressants, antianxiety drugs frequently detected in plasma of older adults admitted for hip fracture, study finds

Of the patient population studied, nearly two-thirds had psychotropic or analgesic drugs or both detected in their blood.
https://immattersacp.org/weekly/archives/2017/03/14/4.htm
14 Mar 2017

MKSAP Quiz: Evaluation for primary hyperparathyroidism

A 67-year-old man is evaluated for a recent diagnosis of primary hyperparathyroidism after an elevated serum calcium level was incidentally detected on laboratory testing. Medical history is significant only for hypertension, and his only medication is ramipril. Following a physical exam and lab studies, what is the most appropriate management of this patient?
https://immattersacp.org/weekly/archives/2017/02/14/3.htm
14 Feb 2017

Act early to counter rise in osteoporosis

Recent studies indicate that late-life bone resiliency has been eroding, and newly released guidelines suggest diagnostic and treatment strategies to counteract that slide among women.
https://immattersacp.org/archives/2017/01/osteoporosis-care.htm
1 Jan 2017

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