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MKSAP Quiz: progressive exertional fatigue and dyspnea

A 77-year-old man with a 5-year history of idiopathic cardiomyopathy is evaluated for progressive exertional fatigue and dyspnea. He has recently stopped carrying groceries in from the car because of his exertional dyspnea. He had an implantable cardioverter-defibrillator placed 3 years ago. Medical history is also significant for hypertension. Medications are lisinopril, 40 mg/d; metoprolol succinate, 25 mg/d; furosemide, 40 mg/d; and spironolactone, 25 mg/d. Following a physical exam and electrocardiogram, what is the most appropriate next step in management?
https://immattersacp.org/weekly/archives/2017/01/31/3.htm
31 Jan 2017

Guidance issued on drug-drug interactions for statins, heart meds

A new statement from the American Heart Association recommends that in patients taking amlodipine combined with simvastatin or lovastatin, the dosage of either statin should not exceed 20 mg/d, and for patients in whom statin-fibrate therapy is indicated, fenofibrate or fenofibric acid is preferred because of a lower rate of drug-drug interactions.
https://immattersacp.org/weekly/archives/2016/10/25/2.htm
25 Oct 2016

Guideline updated to include new drugs for stage C heart failure with reduced ejection fraction

Among other recommendations, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, or an angiotensin receptor-neprilysin inhibitor, along with a beta-blocker and an aldosterone antagonist, is the new recommended therapy to reduce morbidity and mortality in patients with chronic symptomatic heart failure with reduced ejection fraction.
https://immattersacp.org/weekly/archives/2016/05/24/2.htm
24 May 2016

Managing medications in patients with heart failure

Internists can provide a medical home to patients with heart failure so that medications and supplements are regularly assessed and managed, according to experts.
https://immattersacp.org/archives/2017/02/medications.htm
1 Feb 2017

‘Right-to-try’ laws spark debate

This issue covers the ethics of right-to-try laws in the United States, the potential of ransomware to disrupt a physician's office, and conference coverage from infectious disease and cardiology sessions.
https://immattersacp.org/archives/2018/01/right-to-try-laws-spark-debate.htm
1 Jan 2018

New guidelines for dual antiplatelet therapy in patients with CAD

Clinicians should weigh ischemic risks and bleeding risks before adding a P2Y12 inhibitor to aspirin monotherapy or prolonging dual antiplatelet therapy, among other recommendations.
https://immattersacp.org/weekly/archives/2016/04/05/2.htm
5 Apr 2016

Early beta-blocker use may reduce 30-day mortality in patients with acute MI

Patients receiving early beta-blockers had a 30-day mortality rate of 2.3%, compared with 8.6% in those who did not, the study found.
https://immattersacp.org/weekly/archives/2016/09/27/4.htm
27 Sep 2016

Preventive aspirin inflames opinions

Aspirin's long-standing role in cardiovascular health does not resolve its precise benefit in terms of cardiovascular prevention, specifically in patients who haven't had a myocardial infarction or stroke.
https://immattersacp.org/archives/2015/05/aspirin.htm
1 May 2015

Shingles may increase risk of heart attack, stroke

Physicians should inform patients of the risk, as risks of both stroke and heart attack were highest the first year after the onset of shingles and decreased with time.
https://immattersacp.org/weekly/archives/2017/07/11/1.htm
11 Jul 2017

Guidance issued on nonstatin therapies for cholesterol lowering

The goal of the decision pathway was to provide practical guidance for clinicians and patients in situations not covered by the 2013 ACC/AHA guideline until new clinical guidelines on the topic are published.
https://immattersacp.org/weekly/archives/2016/04/05/4.htm
5 Apr 2016

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