The combination of drugs might be a viable treatment strategy for some patients with systemic lupus erythematosus, according to a small, randomized trial.
26 Oct 2021
Lupus can involve multiple organ systems and shares the same, sometimes nonspecific presentation as other conditions. But a diligent internist##mdash;an “excellent generalist” in the words of one expert##mdash;can pick up on the correct diagnosis.
1 Nov 2014
A 30-year-old woman is seen in follow-up. She was diagnosed with systemic lupus erythematosus 12 years ago. She was treated for lupus nephritis, which is now quiescent. What health risk assessment should be performed now?
5 Apr 2022
A 27-year-old man is evaluated for a pruritic rash on his elbows and knees of 3 years' duration. Celiac disease was diagnosed 7 months ago. He started a gluten-free diet, and the diarrhea resolved but the rash has persisted. Following a physical exam and other tests, what is the most appropriate management?
1 Jul 2023
A 30-year-old woman is evaluated during a follow-up visit for systemic lupus erythematosus. She was diagnosed 3 months ago after presenting with pericarditis and arthritis. She was initially treated with prednisone, 40 mg/d, with improvement of her presenting symptoms. The prednisone has been tapered over 3 months to her current dose of 10 mg/d with no recurrence. Following a physical and cardiac exam, what is the most appropriate next step in treating this patient?
6 Mar 2018
A 48-year-old woman is evaluated for easy bruising. She has no history of gingival bleeding, menorrhagia, or bleeding following procedures. Following a physical exam and lab studies, what is the most appropriate diagnostic test?
28 Mar 2023
Celiac disease should be part of the differential diagnosis for several classic clinical presentations, but atypical symptoms, including constipation, can cause doctors to overlook some patients.
1 Feb 2023
A 19-year-old woman is evaluated for a 2-week history of fatigue, poor appetite, arthralgia of the hands and knees, and a rash, all of which appeared 1 day after a beach trip. After physical exam, lab studies, and kidney ultrasound, what is the most appropriate diagnostic test to perform next?
17 Jan 2023
Recalls, warnings, and approvals.
1 May 2011
A multidrug, multitarget regimen was superior to intravenous cyclophosphamide as induction therapy for lupus nephritis, according to a randomized, controlled trial.
11 Nov 2014