Anti-double-stranded DNA antibodies are highly specific for systemic lupus erythematosus (SLE). ... In addition, more than 99% of patients with SLE have antinuclear antibodies, which are absent in this patient.
Nonspecific symptoms, including fatigue and muscle pain, are commonplace in most internists' practice, but sometimes, especially in women, they can be the result of a larger problem: lupus. ... Do you handle long-term management of patients with lupus in
Sjögren's syndrome may occur in isolation or secondary to other autoimmune disorders, such as lupus, rheumatoid arthritis or scleroderma. ... At several points in the article and in your editorial column, fibromyalgia is referenced as an autoimmune
Sjögren's often presents like other autoimmune diseases, such as lupus, rheumatoid arthritis and fibromyalgia, and may even overlap with those or other conditions, such as systemic sclerosis. ... Sjögren's syndrome is genetically, serologically and
Although associated with systemic lupus erythematosus (SLE), it is a distinct disorder that may present with different cutaneous findings than those usually associated with SLE. ... Patients with subacute cutaneous lupus erythematosus have annular scaly
Although this young patient may have an autoimmune inflammatory arthritis such as systemic lupus erythematosus or rheumatoid arthritis, he has evidence of an arthritis-dermatitis syndrome and should be evaluated for
Methotrexate is appropriate for management of rheumatoid arthritis. However, rheumatoid arthritis and systemic lupus erythematosus are not associated with involvement of the distal interphalangeal joints and deforming arthritis, respectively, which
Hanrahan noted. Common inflammatory/autoimmune causes of fever are adult-onset Still's disease, systemic lupus erythematosus, and polyarteritis nodosa.
Antihistone antibodies occur frequently in patients with either systemic or drug-induced lupus erythematosus. ... This patient's disease is more consistent with hypersensitivity vasculitis without specific features of drug-induced lupus (for example,
Bullous lupus erythematosus is a rare form of cutaneous lupus in which patients develop small blisters within and in addition to their other cutaneous lupus lesions; the blisters are generally small ... Signs of systemic lupus erythematosus should be