Patients with first-time venous thromboembolism (VTE) who weighed 120 kg or more and had a body mass index (BMI) of 40 kg/m2 or more were not at higher risk for bleeding or recurrent VTE with direct-acting oral anticoagulants (DOACs) versus warfarin.
9 Nov 2021
A 68-year-old man is evaluated for a 6-month history of intermittent claudication. His symptoms have been slowly progressive but are not life limiting. Medical history is significant for hypertension, hyperlipidemia, and carotid artery stenosis treated with left carotid endarterectomy. He is a former smoker but quit 10 years ago. Following a physical exam and lab studies, what is the most appropriate treatment to reduce this patient's cardiovascular risk?
23 Aug 2022
Two new analyses of recent cardiology trials highlighted the prevalence and potential adverse effects of nonadherence to medications.
16 Aug 2022
The U.S. Preventive Services Task Force reviewed trials published since 2017 but did not deem them strong enough to show evidence of benefit or harm.
1 Feb 2022
Among other recommendations, the new guidelines from the American Society of Hematology suggest offering home treatment to low-risk patients with deep venous thrombosis (DVT) or pulmonary embolism (PE).
20 Oct 2020
This update covers the approval of an oral medication to reduce the risk of stroke and embolism in atrial fibrillation and the first generic version of esomeprazole.
1 Apr 2015
In a randomized trial at 16 primary care clinics in Massachusetts, rates of new afib diagnosis at one year were 1.72% with afib screening of older patients using a single-lead electrocardiogram versus 1.59% with usual care.
8 Mar 2022
A 26-year-old woman seeks preconception counseling. She has a history of mitral stenosis and underwent mitral valve replacement with a tilting-disc mechanical prosthesis 5 years ago. Following a physical exam, lab studies, and electrocardiogram, what is the most appropriate anticoagulation regimen for this patient during the first trimester?
23 Jun 2020
Primary care physicians play a crucial role in ongoing anticoagulation management, including educating patients about the signs of venous thromboembolism.
1 Apr 2022
Patients taking apixaban, dabigatran, or rivaroxaban had lower rates of hip and vertebral fractures than those taking warfarin, with no difference seen between the direct oral anticoagulants (DOACs).
19 May 2020