American College of Physicians: Internal Medicine — Doctors for Adults ®


ACP Diabetes Monthly

Welcome to this month's issue of ACP Diabetes Monthly, an update for internists published by the American College of Physicians.

In the News for the month of July 2016


Liraglutide may offer high-risk patients protection from CV events, death, study finds

The Liraglutide Effect and Action in Diabetes: Evaluation of Cardiovascular Outcome Results (LEADER) trial, which was funded by Novo Nordisk and the National Institutes of Health, randomized 9,340 patients ages 50 years and older to 1.8 mg of liraglutide per day via injection or placebo in addition to standard care. More...

Thiazolidinedione add-ons associated with less CV risk, study finds

The U.K.-based retrospective cohort study used a database that linked national hospitalization and mortality data for people who were prescribed second-line regimens after metformin. More...

Socioeconomic status appears linked to mortality in patients with type 2 diabetes

The study looked at data from the Sweden National Diabetes Register to determine what patient characteristics were related to all-cause mortality or death from cardiovascular-, diabetes-, or cancer-related causes. More...

Test yourself

MKSAP quiz: Inpatient glycemic control

This month's quiz asked readers to determine optimal glycemic control for a man with type 2 diabetes who is admitted to the hospital for evaluation of substernal chest pain. More...

From Annals of Internal Medicine

Pioglitazone improved NASH markers in patients with type 2 or prediabetes and NASH

One hundred one patients with prediabetes or type 2 diabetes and biopsy-proven nonalcoholic steatohepatitis (NASH) were prescribed a hypocaloric diet and randomized to 45 mg of pioglitazone per day or placebo for 18 months. After 18 months, pioglitazone was prescribed open label to all patients without histologic resolution of NASH. More...

From ACP Journal Club

Review: In diabetes, benefits of lowering BP depend on baseline BP being 140 mm Hg or more

Hypertension treatment reduced mortality and myocardial infarction in diabetic patients with a systolic blood pressure of at least 140 mm Hg, a systematic review and meta-analysis found. However, in patients with lower baseline blood pressure (BP), treatment didn't affect overall mortality and was associated with increased cardiovascular mortality. More...

From ACP Internist

New insulins present benefits, challenges

The July/August ACP Internist summarizes expert advice on treating diabetes with new types of insulin. More...

Keeping tabs

Spotlight on renal side effects

Renal side effects of diabetes drugs were in the news in the past month, with one industry-funded study finding an association between empagliflozin and slower progression of kidney disease and the FDA strengthening an existing warning on risk of acute kidney injury with canagliflozin and dapagliflozin. More...

Physician editor: David V. O'Dell, MD, FACP

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About ACP Diabetes Monthly

ACP Diabetes Monthly is a monthly newsletter produced by the staff of ACP Internist. It is automatically sent to all College members who have an e-mail address on file with ACP.

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Test yourself

A 74-year-old woman is evaluated during a routine examination. Her medical history is significant for hypertension and obesity. She is a former smoker, stopping 5 years ago. Medications are amlodipine, lisinopril, and aspirin. Following a physical exam and ankle-brachial index score, what is the most appropriate management?

Find the answer

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