American College of Physicians: Internal Medicine — Doctors for Adults ®


Crossed Words: Elements of illness

From the October ACP Internist, copyright 2013 by the American College of Physicians

By Justin Vader, MD, ACP Resident/Fellow Member

Answers to clues are placed horizontally in rows to reveal an answer written vertically. Unlike the familiar acrostic puzzle format, the final answer can be in any column.

Horizontal clues

1) Osborne waves when you feel this way

2) Hepatotoxin of the sago palm

3) Supreme Court of the U.S. decided this “individual” stays in ACA

4) Single sort of superficial skin surgery

5) Fab-ulous treatment for a drug’s toxicity

6) Account for cumulative consumption e.g., pack-years

7) Skin atlas ... and there is an app for that

Find in the vertical columns: Toxin cause of the “ouch-ouch” sickness

Puzzle grid

Answer: Cadmium

Puzzle answer

Cadmium is found in much of the environment, and the general population may be exposed to cadmium daily through food, cigarette smoke, drinking water and air. The most sensitive targets of cadmium toxicity are the kidney and bone following oral exposure, and kidney and lung following inhalation exposure.

The effects observed in humans include renal tubular damage, glomerular damage, decreases in bone mineralization, increased risk of bone fractures, decreased lung function, and emphysema. These effects typically occur after long term exposure to cadmium, which has a half-time in the human body of more than 26 years. (Source: CDC, accessed online.)

Crossed Words: Elements of illness


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