Chromosome is where the heart is


Answers to clues are placed horizontally in rows to reveal an answer written vertically. Unlike the familiar acrostic puzzle format, the final answer can be in any column.

Horizontal clues

1) Rostrae

2) Normally 136-145 mEq/L

3) Stands out as a sign of muscular dystrophy

4) Togavirus ________’nyong

5) HACEK target

6) Viscera to the layman

Find in the vertical columns: Eponymous syndrome characterized by short stature, webbed neck, hypertelorism, chest deformities, and autosomal dominant inheritance (Table 1)

Answer: Noonan syndrome

(Table 2) Noonan syndrome is a disease that can be passed down through families (inherited). It causes abnormal development in many parts of the body. Noonan syndrome used to be called Turner-like syndrome.

Noonan syndrome is an autosomal dominant condition linked to defects in several genes. Symptoms include delayed puberty, down-slanting or wide-set eyes, hearing loss (varies), low-set or abnormally shaped ears, mild intellectual disability in about 25% of cases, ptosis, short stature, small penis, undescended testicles, unusual chest shape (usually pectus excavatum), and a webbed and short-appearing neck. (Source: National Library of Medicine, online. )